Despite increasing evidence of cannabinoids’ analgesic properties, concerns regarding its potential for abuse limit its utility in pain management. The present study posits a solution to such valid and thoughtful concern. GAT211 is a novel compound that positively acts on CB1 receptors to decrease pain. Unlike other cannabinoids, treatment with GAT211 did not produce tolerance or dependence despite alleviating pain.
Cannabinoid decreased pain without producing tolerance or dependence
