Anti-Anxiety Effects of Cannabidiol

Linares, I. M., Zuardi, A. W., Pereira, L. C., Queiroz, R. H., Mechoulam, R., Guimarães, F. S., & Crippa, J. A. (2018). Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Brazilian Journal of Psychiatry, (AHEAD).

This study examined the anti-anxiety effect of cannabidiol using the Simulated Public Speaking Test to induce anxiety and the Visual Analogue Mood Scale to assess subjective ratings of anxiety. The authors also sought to identify the optimal dose of cannabidiol that would elicit the greatest anti-anxiety effect. The results show that an intermediate dose of cannabidiol (300 mg) produces a stronger anti-anxiety effect compared to either the lower (150 mg) or higher (600 mg) dose.

View This Research