Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats
Hay, Gracie L., et al. "Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats." Journal of Psychopharmacology 32.12 (2018): 1369-1378.
Cannabidiol, a non-intoxicating constituent of cannabis, has been implicated as a possible anxiolytic and anti-epileptic with the FDA recently approving a drug to treat epilepsy with cannabidiol as its primary ingredient. The present study aims to examine cannabidiol’s effect on methamphetamine addiction using a rat model. The results showed that CBD at a dose of 80 mg/kg decreased the rats’ motivation to self-administer methamphetamine. Despite such exciting result, one must be careful interpreting this finding because the mechanism for this effect is still unknown. Consequently, further research is warranted to discover the mechanism underlying this effect.View This Research