Chavez J, Le AA, Quintanilla J, Tagne AM, Piomelli D, Lynch G, Gall CM. (2022)  Microglia depletion selectively eliminates a singular form of hippocampal long-term potentiation. BioRxiv. doi: https://doi.org/10.1101/2022.07.29.501926

Le AA, Lauterborn JC, Jia Y, Wang W, Cox C, Gall CM, Lynch G.  (2022) Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases. Nature Neurosci., 25(2):180-190. PMID: 35087246

Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, Wood M, Green K, Piomelli D. (2022) Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood. Biol Psychiatry. May 10:S0006-3223(22)01237-9. PMID: 35750512 Data is available at: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213734

Farrell, MR, Ye, Q, Xie, Y, Esteban, JSD, Mahler, SV. (2022) Ventral Pallidum GABA Neurons Bidirectionally Control Opioid Relapse Across Rat Behavioral Models. Addiction Neuroscience. https://doi.org/10.1016/j.addicn.2022.100026

Quintanilla J, Jia Y, Lauterborn JC, Pruess BS, Le AA, Cox CD, Gall CM, Lynch G, Gunn BG. (2022) Novel types of frequency filtering in the lateral perforant path projections to the dentate gyrus.  J Physiol 600.16; pp 3865–3896. PMID: 35852108

Torrens, A, Roy, P, Lin, L, Vu, C, Grimes, D, Inshishian, VC, Montesinos, JS, Ahmed, F, Mahler, SV, Huestis, MA, Das, A, Piomelli, D. (2022) Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats. Cannabis and Cannabinoid Research. doi: 10.1089/can.2021.0205. PMID: 35353551


Amani M, Lauterborn JC, Le AA, Cox BM, Wang W, Quintanilla J, Cox CD, Gall CM, Lynch G. (2021) Rapid Aging in the Perforant Path Projections to the Rodent Dentate Gyrus. J Neurosci. 2021;41(10):2301-12. Epub 2021/01/31. PMID: 33514675.

Gall CM, Le AA, Lynch G. (2021) Sex differences in synaptic plasticity underlying learning. J Neurosci Res.  2021/04/14. PubMed PMID: 33847004.

Lawson, KA, Flores, AY, Hokenson, RE, Ruiz, CM, Mahler, SV. (2021) Nucleus Accumbens Chemogenetic Inhibition Suppresses Amphetamine-Induced Ultrasonic Vocalizations in Male and Female Rats. Brain Sciences. 2021 Sep 22;11(10):1255. PMID: 34679320

Le AA, Quintanilla J, Amani M, Piomelli D, Gall CM, Lynch G. (2021) Sexually dimorphic effects of adolescent THC on hippocampal synaptic plasticity and episodic memory in rodents. Neurobiol. Disease.  Epub 2021/11/24. PMID: 34838664.

Levis, SC, Bentzley, BS, Molet, J, Bolton, JL, Perrone, CR, Baram, TZ, & Mahler, SV. (2021) On the early-life origins of vulnerability to opioid addiction. Molecular Psychiatry. 2021 Aug;26(8):4409-4416. Epub 2019 Dec 10. PMID: 31822817

Levis, SC, Mahler, SV, Baram, TZ. (2021) The developmental origins of opioid use disorder and its comorbidities. Frontiers in Human Neuroscience. Feb 11;15:601905. PMID: 33643011

Ruiz, CM, Torrens, A, Castillo, E, Perrone, CR, Cevallos, J, Inshishian, V, Harder, E, Justeson, D, Huestis, MA, Swarup, V, Piomelli, D, Mahler, SV. (2021) Pharmacokinetic, behavioral, and brain activity impacts of Δ9-tetrahydrocannabinol in adolescent male and female rats. Neuropsychopharmacology. 2021 Apr;46(5):959-969. PMID: 32927465.

Ruiz, CM, Torrens, A, Lallai, V, Castillo, E, Manca, L, Martinez, MX, Justeson, DN, Fowler, CD, Piomelli, D, Mahler SV. (2021) Pharmacokinetic and pharmacodynamic properties of aerosolized (“vaped”) THC in adolescent male and female rats. Psychopharmacology, 238(12):3595-3605. PMID: 34495367

Quintanilla J, Cox BM, Gall CM, Mahler SV, Lynch G. (2021) Retrograde enhancement of episodic learning by a postlearning stimulus. Learn Mem. 2021;28(3):82-6. Epub 2021/02/18. PMID: 33593926.  


Brodnik, ZD, Xu, W, Batra, A, Lewandowski, S, Ruiz, CM, Mortensen, O, Kortagere, S, Mahler, SV, España, RA. (2020) Chemogenetic manipulation of dopamine neurons dictates cocaine potency at distal dopamine transporters. Journal of Neuroscience, 40(44), 8767-8779. PMID: 33046544

James, MH & Mahler, SV (2020) Do striatal push/pull circuits hold the key to relapsing heroin addiction? Neuropsychopharmacology, 45(8), 1243-1244. PMID: 31974443

Torrens, A, Vozella, V, Huff, H, McNeil, B, Ahmed, F, Ghidini, A, Mahler, SV, Huestis, MA, Das, A, Piomelli, D (2020) Comparative pharmacokinetics of Δ9-tetrahydrocannabinol in adolescent and adult male mice. Journal of Pharmacology and Experimental Therapeutics, 374(1), 151-160. PMID: 34495367


Bonaventura, J, Eldridge, MA, Hu, F, Gomez, JL, Sanchez-Soto, M, Abramyan, AM, Lam, S, Boehm, M, Ruiz, CM, Farrell, MR, Moreno, A, Faress, IMG, Andersen, N, Lin, JY, Moaddel, R, Morris, P, Shi, L, Sibley, DR, Mahler, SV, Nabavi, S, Pomper, MG, Bonci, A, Horti, AG, Richmond, BJ & Michaelides, M. (2019) High-potency ligands for DREADD imaging and activation. Nature Communications 10, 4627. PMID: 31604917

Mahler, SV, Brodnik, ZD, Cox, BM, Buchta, WC, Bentzely, BS, Quintanilla, J, Cope, ZA, Lin, EC, Riedy, MD, Scofield, MD, Messinger, J, Ruiz, CM, Riegel, AC, Espana, RA, Aston-Jones, G. (2019) Chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse. Journal of Neuroscience, 39(3), 503-518. PMID: 30446532

Vozella V, Zibardi C, Ahmed F, Piomelli D. (2019) Fast and Sensitive Quantification of Δ9-Tetrahydrocannabinol and Its Main Oxidative Metabolites by Liquid Chromatography/Tandem Mass Spectrometry. Cannabis Cannabinoid Res. 2019 Jun 14;4(2):110-123. PMID: 31236476.


Schoch, H, Huerta, MY, Ruiz, CM, Farrell, MR, Jung, KM, Huang, JJ, Campbell, RR, Piomelli, D & Mahler, SV. (2018) Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. 235pages 121–134

Mitchell, MR, Berridge, KC, & Mahler, SV. (2018) Endocannabinoid-enhanced “liking” in nucleus accumbens shell hedonic hotspot requires endogenous opioid signals. Cannabis & Cannabinoid Research, 3(1), 166-170. doi: 10.1089/can.2018.0021